Regular Tai Chi Chuan exercise improves T cell helper function of patients with type 2 diabetes mellitus with an increase in T-bet transcription factor and IL-12 production.
Tai Chi exercises can improve the control of type 2 diabetes, suggests a small study. The research team assessed the impact of a 12 week programme of Tai Chi exercises on the T helper cell activity of 30 patients with type 2 diabetes and 30 healthy people of the same age.
T cells are a key component of the body’s immune system, producing powerful chemicals, including Interleukins, which alter the immune response. Type 2 diabetes is associated with chronic inflammation, caused by excessive glucose in the blood (hyperglycaemia).
After the 12 week programme glycated haemoglobin (when excess blood sugar combines with the oxygen transporter in red blood cells) levels fell significantly from 7.59% to 7.16 in the diabetic patients.
And levels of interleukin-12, which boosts the immune response, doubled. Levels of interleukin-4, which suppresses the immune response, fell. T cell activity also significantly increased.
Strenuous physical activity depresses the immune system response, but moderate exercise seems to have the opposite effect, say the authors. Tai Chi is classified as moderate exercise.
Previous research has shown that it boosts cardiovascular and respiratory function, as well as improving flexibility and relieving stress, they add. Tai Chi may prompt a fall in blood glucose levels, or improve blood glucose metabolism, sparking a drop in the inflammatory response.
Alternatively, the exercise may boost fitness levels and the feeling of wellbeing, which may then boost the health of the immune system, they suggest.
Reference: S-H Yeh, H Chuang, L-W Lin, C-Y Hsiao, P-W Wang, R-T Liu, K D Yang “Regular Tai Chi Chuan exercise improves T cell helper function of patients with type 2 diabetes mellitus with an increase in T-bet transcription factor and IL-12 production” Br J Sports Med 2009;43:845-850 Published Online First: 2 April 2008 doi:10.1136/bjsm.2007.043562